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Structure-Activity Relationship of Synthetic 2-Phenylnaphthalenes with Hydroxyl Groups that Inhibit Proliferation and Induce Apoptosis of MCF-7 Cancer Cells

In this study, six 2-phenylnaphthalenes with hydroxyl groups were synthesized in high yields by the demethylation of the corresponding methoxy-2-phenylnaphthalenes, and one 2-phenylnaphthalene with an amino group was obtained by hydrogenation. All of the 2-phenylnaphthalene derivatives were evaluate...

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Detalles Bibliográficos
Autores principales: Chang, Chi-Fen, Ke, Ci-Yi, Wu, Yang-Chang, Chuang, Ta-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619615/
https://www.ncbi.nlm.nih.gov/pubmed/26492346
http://dx.doi.org/10.1371/journal.pone.0141184