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Ecto-5’-Nucleotidase Overexpression Reduces Tumor Growth in a Xenograph Medulloblastoma Model

BACKGROUND: Ecto-5’-nucleotidase/CD73 (ecto-5’-NT) participates in extracellular ATP catabolism by converting adenosine monophosphate (AMP) into adenosine. This enzyme affects the progression and invasiveness of different tumors. Furthermore, the expression of ecto-5’-NT has also been suggested as a...

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Detalles Bibliográficos
Autores principales: Cappellari, Angélica R., Pillat, Micheli M., Souza, Hellio D. N., Dietrich, Fabrícia, Oliveira, Francine H., Figueiró, Fabrício, Abujamra, Ana L., Roesler, Rafael, Lecka, Joanna, Sévigny, Jean, Battastini, Ana Maria O., Ulrich, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619639/
https://www.ncbi.nlm.nih.gov/pubmed/26491983
http://dx.doi.org/10.1371/journal.pone.0140996