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Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes

Recently we identified multiple suramin-sensitivity genes with a genome wide screen in Trypanosoma brucei that includes the invariant surface glycoprotein ISG75, the adaptin-1 (AP-1) complex and two deubiquitylating enzymes (DUBs) orthologous to ScUbp15/HsHAUSP1 and pVHL-interacting DUB1 (type I), d...

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Detalles Bibliográficos
Autores principales: Zoltner, Martin, Leung, Ka Fai, Alsford, Sam, Horn, David, Field, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619645/
https://www.ncbi.nlm.nih.gov/pubmed/26492041
http://dx.doi.org/10.1371/journal.ppat.1005236