Differences in Expression Level of Helios and Neuropilin-1 Do Not Distinguish Thymus-Derived from Extrathymically-Induced CD4(+)Foxp3(+) Regulatory T Cells

Helios transcription factor and semaphorin receptor Nrp-1 were originally described as constitutively expressed at high levels on CD4(+)Foxp3(+) T regulatory cells of intrathymic origin (tTregs). On the other hand, CD4(+)Foxp3(+) Tregs generated in the periphery (pTregs) or induced ex vivo (iTregs)...

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Detalles Bibliográficos
Autores principales: Szurek, Edyta, Cebula, Anna, Wojciech, Lukasz, Pietrzak, Maciej, Rempala, Grzegorz, Kisielow, Pawel, Ignatowicz, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619666/
https://www.ncbi.nlm.nih.gov/pubmed/26495986
http://dx.doi.org/10.1371/journal.pone.0141161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619666/
https://www.ncbi.nlm.nih.gov/pubmed/26495986
http://dx.doi.org/10.1371/journal.pone.0141161

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