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Characterization of Dnmt1 Binding and DNA Methylation on Nucleosomes and Nucleosomal Arrays

The packaging of DNA into nucleosomes and the organisation into higher order structures of chromatin limits the access of sequence specific DNA binding factors to DNA. In cells, DNA methylation is preferentially occuring in the linker region of nucleosomes, suggesting a structural impact of chromati...

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Detalles Bibliográficos
Autores principales: Schrader, Anna, Gross, Thomas, Thalhammer, Verena, Längst, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619679/
https://www.ncbi.nlm.nih.gov/pubmed/26496704
http://dx.doi.org/10.1371/journal.pone.0140076