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Characterization of Dnmt1 Binding and DNA Methylation on Nucleosomes and Nucleosomal Arrays
The packaging of DNA into nucleosomes and the organisation into higher order structures of chromatin limits the access of sequence specific DNA binding factors to DNA. In cells, DNA methylation is preferentially occuring in the linker region of nucleosomes, suggesting a structural impact of chromati...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619679/ https://www.ncbi.nlm.nih.gov/pubmed/26496704 http://dx.doi.org/10.1371/journal.pone.0140076 |