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Effects of the Interactions between Dust Exposure and Genetic Polymorphisms in Nalp3, Caspase-1, and IL-1β on the Risk of Silicosis: A Case-Control Study

OBJECTIVES: To evaluate the effects of the interactions between polymorphisms in Nalp3, caspase-1, and interleukin(IL)-1β genes and occupational dust exposure on the risk of silicosis. METHODS: We conducted a population-based case-control study in a large iron mine in China. Between January 2006 and...

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Detalles Bibliográficos
Autores principales: Weng, Shaofan, Wang, Lihua, Rong, Yi, Liu, Yuewei, Wang, Xin, Guan, Hongyu, Chen, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619690/
https://www.ncbi.nlm.nih.gov/pubmed/26496436
http://dx.doi.org/10.1371/journal.pone.0140952