Cargando…

Altered Gene Expression Associated with microRNA Binding Site Polymorphisms

Allele-specific gene expression associated with genetic variation in regulatory regions can play an important role in the development of complex traits. We hypothesized that polymorphisms in microRNA (miRNA) response elements (MRE-SNPs) that either disrupt a miRNA binding site or create a new miRNA...

Descripción completa

Detalles Bibliográficos
Autores principales: Võsa, Urmo, Esko, Tõnu, Kasela, Silva, Annilo, Tarmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619707/
https://www.ncbi.nlm.nih.gov/pubmed/26496489
http://dx.doi.org/10.1371/journal.pone.0141351