A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis

The co-chaperone BAG3, in complex with the heat shock protein HSPB8, plays a role in protein quality control during mechanical strain. It is part of a multichaperone complex that senses damaged cytoskeletal proteins and orchestrates their seclusion and/or degradation by selective autophagy. Here we...

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Detalles Bibliográficos
Autores principales: Fuchs, Margit, Luthold, Carole, Guilbert, Solenn M., Varlet, Alice Anaïs, Lambert, Herman, Jetté, Alexandra, Elowe, Sabine, Landry, Jacques, Lavoie, Josée N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619738/
https://www.ncbi.nlm.nih.gov/pubmed/26496431
http://dx.doi.org/10.1371/journal.pgen.1005582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619738/
https://www.ncbi.nlm.nih.gov/pubmed/26496431
http://dx.doi.org/10.1371/journal.pgen.1005582

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