Inhibition of HIV-1 Viral Infection by an Engineered CRISPR Csy4 RNA Endoribonuclease

The bacterial defense system CRISPR (clustered regularly interspaced short palindromic repeats) has been explored as a powerful tool to edit genomic elements. In this study, we test the potential of CRISPR Csy4 RNA endoribonuclease for targeting HIV-1. We fused human codon-optimized Csy4 endoribonuc...

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Detalles Bibliográficos
Autores principales: Guo, Rui, Wang, Hong, Cui, Jiuwei, Wang, Guanjun, Li, Wei, Hu, Ji-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619743/
https://www.ncbi.nlm.nih.gov/pubmed/26495836
http://dx.doi.org/10.1371/journal.pone.0141335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619743/
https://www.ncbi.nlm.nih.gov/pubmed/26495836
http://dx.doi.org/10.1371/journal.pone.0141335

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