Downregulation of Choline Kinase-Alpha Enhances Autophagy in Tamoxifen-Resistant Breast Cancer Cells

Choline kinase-α (Chk-α) and autophagy have gained much attention, as they relate to the drug-resistance of breast cancer. Here, we explored the potential connection between Chk-α and autophagy in the mechanisms driving to tamoxifen (TAM) resistance, in estrogen receptor positive (ER+) breast cancer...

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Detalles Bibliográficos
Autores principales: Kim, Hoe Suk, Tian, Lianji, Jung, Minji, Choi, Sul Ki, Sun, Yujin, Kim, Hyeonjin, Moon, Woo Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619766/
https://www.ncbi.nlm.nih.gov/pubmed/26496360
http://dx.doi.org/10.1371/journal.pone.0141110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619766/
https://www.ncbi.nlm.nih.gov/pubmed/26496360
http://dx.doi.org/10.1371/journal.pone.0141110

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