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An Exploration of the Universe of Polyglutamine Structures

Deposits of misfolded proteins in the human brain are associated with the development of many neurodegenerative diseases. Recent studies show that these proteins have common traits even at the monomer level. Among them, a polyglutamine region that is present in huntingtin is known to exhibit a corre...

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Detalles Bibliográficos
Autores principales: Gómez-Sicilia, Àngel, Sikora, Mateusz, Cieplak, Marek, Carrión-Vázquez, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619799/
https://www.ncbi.nlm.nih.gov/pubmed/26495838
http://dx.doi.org/10.1371/journal.pcbi.1004541