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An Exploration of the Universe of Polyglutamine Structures
Deposits of misfolded proteins in the human brain are associated with the development of many neurodegenerative diseases. Recent studies show that these proteins have common traits even at the monomer level. Among them, a polyglutamine region that is present in huntingtin is known to exhibit a corre...
Autores principales: | Gómez-Sicilia, Àngel, Sikora, Mateusz, Cieplak, Marek, Carrión-Vázquez, Mariano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619799/ https://www.ncbi.nlm.nih.gov/pubmed/26495838 http://dx.doi.org/10.1371/journal.pcbi.1004541 |
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