Inhibition of P-Selectin and PSGL-1 Using Humanized Monoclonal Antibodies Increases the Sensitivity of Multiple Myeloma Cells to Bortezomib

Multiple myeloma (MM) is a plasma cell malignancy localized in the bone marrow. Despite the introduction of novel therapies majority of MM patients relapse. We have previously shown that inhibition of P-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) play a key role in proliferation of MM and...

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Detalles Bibliográficos
Autores principales: Muz, Barbara, Azab, Feda, de la Puente, Pilar, Rollins, Scott, Alvarez, Richard, Kawar, Ziad, Azab, Abdel Kareem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619821/
https://www.ncbi.nlm.nih.gov/pubmed/26539491
http://dx.doi.org/10.1155/2015/417586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619821/
https://www.ncbi.nlm.nih.gov/pubmed/26539491
http://dx.doi.org/10.1155/2015/417586

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