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Arctigenin, a Potent Ingredient of Arctium lappa L., Induces Endothelial Nitric Oxide Synthase and Attenuates Subarachnoid Hemorrhage-Induced Vasospasm through PI3K/Akt Pathway in a Rat Model

Upregulation of protein kinase B (PKB, also known as Akt) is observed within the cerebral arteries of subarachnoid hemorrhage (SAH) animals. This study is of interest to examine Arctigenin, a potent antioxidant, on endothelial nitric oxide synthase (eNOS) and Akt pathways in a SAH in vitro study. Ba...

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Detalles Bibliográficos
Autores principales: Chang, Chih-Zen, Wu, Shu-Chuan, Chang, Chia-Mao, Lin, Chih-Lung, Kwan, Aij-Lie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619842/
https://www.ncbi.nlm.nih.gov/pubmed/26539501
http://dx.doi.org/10.1155/2015/490209