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PPARα Agonist WY-14643 Induces SIRT1 Activity in Rat Fatty Liver Ischemia-Reperfusion Injury

Ischemia-reperfusion injury (IRI) remains a frequent complication in surgery, especially in case of steatotic livers that present decreased tolerance towards IRI. Apart from its major role in metabolism, activation of peroxisome proliferator-activated receptor α (PPARα) has been related with positiv...

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Detalles Bibliográficos
Autores principales: Pantazi, Eirini, Folch-Puy, Emma, Bejaoui, Mohamed, Panisello, Arnau, Varela, Ana Teresa, Rolo, Anabela Pinto, Palmeira, Carlos Marques, Roselló-Catafau, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619850/
https://www.ncbi.nlm.nih.gov/pubmed/26539534
http://dx.doi.org/10.1155/2015/894679