HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse

piRNAs are critical for transposable element (TE) repression and germ cell survival during the early phases of spermatogenesis, however, their role in adult germ cells and the relative importance of piRNA methylation is poorly defined in mammals. Using a mouse model of HEN methyltransferase 1 (HENMT...

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Detalles Bibliográficos
Autores principales: Lim, Shu Ly, Qu, Zhi Peng, Kortschak, R. Daniel, Lawrence, David M., Geoghegan, Joel, Hempfling, Anna-Lena, Bergmann, Martin, Goodnow, Christopher C., Ormandy, Christopher J., Wong, Lee, Mann, Jeff, Scott, Hamish S., Jamsai, Duangporn, Adelson, David L., O’Bryan, Moira K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619860/
https://www.ncbi.nlm.nih.gov/pubmed/26496356
http://dx.doi.org/10.1371/journal.pgen.1005620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619860/
https://www.ncbi.nlm.nih.gov/pubmed/26496356
http://dx.doi.org/10.1371/journal.pgen.1005620

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