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How to Choose In Vitro Systems to Predict In Vivo Drug Clearance: A System Pharmacology Perspective
The use of in vitro metabolism data to predict human clearance has become more significant in the current prediction of large scale drug clearance for all the drugs. The relevant information (in vitro metabolism data and in vivo human clearance values) of thirty-five drugs that satisfied the entry c...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619875/ https://www.ncbi.nlm.nih.gov/pubmed/26539530 http://dx.doi.org/10.1155/2015/857327 |