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Automatic Prediction of Protein 3D Structures by Probabilistic Multi-template Homology Modeling

Homology modeling predicts the 3D structure of a query protein based on the sequence alignment with one or more template proteins of known structure. Its great importance for biological research is owed to its speed, simplicity, reliability and wide applicability, covering more than half of the resi...

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Detalles Bibliográficos
Autores principales: Meier, Armin, Söding, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619893/
https://www.ncbi.nlm.nih.gov/pubmed/26496371
http://dx.doi.org/10.1371/journal.pcbi.1004343