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Modulating p56Lck in T-Cells by a Chimeric Peptide Comprising Two Functionally Different Motifs of Tip from Herpesvirus saimiri

The Lck interacting protein Tip of Herpesvirus saimiri is responsible for T-cell transformation both in vitro and in vivo. Here we designed the chimeric peptide hTip-CSKH, comprising the Lck specific interacting motif CSKH of Tip and its hydrophobic transmembrane sequence (hTip), the latter as a vec...

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Detalles Bibliográficos
Autores principales: Vernot, Jean-Paul, Perdomo-Arciniegas, Ana María, Pérez-Quintero, Luis Alberto, Martínez, Diego Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619936/
https://www.ncbi.nlm.nih.gov/pubmed/26539553
http://dx.doi.org/10.1155/2015/395371