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EGCG Attenuates Uric Acid-Induced Inflammatory and Oxidative Stress Responses by Medicating the NOTCH Pathway

Background. The aim of this study is to investigate whether (-)-epigallocatechin-3-gallate (EGCG) can prevent the UA-induced inflammatory effect of human umbilical vein endothelial cells (HUVEC) and the involved mechanisms in vitro. Methods. HUVEC were subjected to uric acid (UA) with or without EGC...

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Detalles Bibliográficos
Autores principales: Xie, Hua, Sun, Jianqin, Chen, Yanqiu, Zong, Min, Li, Shijie, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619967/
https://www.ncbi.nlm.nih.gov/pubmed/26539255
http://dx.doi.org/10.1155/2015/214836