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Sympathetic autonomic dysfunction and impaired cardiovascular performance in higher risk surgical patients: implications for perioperative sympatholysis

OBJECTIVE: Recent perioperative trials have highlighted the urgent need for a better understanding of why sympatholytic drugs intended to reduce myocardial injury are paradoxically associated with harm (stroke, myocardial infarction). We hypothesised that following a standardised autonomic challenge...

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Detalles Bibliográficos
Autores principales: Whittle, John, Nelson, Alexander, Otto, James M, Stephens, Robert C M, Martin, Daniel S, Sneyd, J Robert, Struthers, Richard, Minto, Gary, Ackland, Gareth L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620232/
https://www.ncbi.nlm.nih.gov/pubmed/26512327
http://dx.doi.org/10.1136/openhrt-2015-000268