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Predicting Drug-Target Interactions via Within-Score and Between-Score

Network inference and local classification models have been shown to be useful in predicting newly potential drug-target interactions (DTIs) for assisting in drug discovery or drug repositioning. The idea is to represent drugs, targets, and their interactions as a bipartite network or an adjacent ma...

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Detalles Bibliográficos
Autores principales: Shi, Jian-Yu, Liu, Zun, Yu, Hui, Li, Yong-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620248/
https://www.ncbi.nlm.nih.gov/pubmed/26543857
http://dx.doi.org/10.1155/2015/350983