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Identification of high-affinity VEGFR3-binding peptides through a phage-displayed random peptide library

OBJECTIVE: Vascular endothelial growth factor (VEGF) interaction with its receptor, VEGFR-3/Flt-4, regulates lymphangiogenesis. VEGFR-3/Flt-4 expression in cancer cells has been correlated with clinical stage, lymph node metastasis, and lymphatic invasion. The objective of this study is to identify...

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Detalles Bibliográficos
Autores principales: Shi, Li-Feng, Wu, Yan, Li, Cai-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620370/
https://www.ncbi.nlm.nih.gov/pubmed/26197772
http://dx.doi.org/10.3802/jgo.2015.26.4.327