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Temporal Identification of Dysregulated Genes and Pathways in Clear Cell Renal Cell Carcinoma Based on Systematic Tracking of Disrupted Modules

Objective. The objective of this work is to identify dysregulated genes and pathways of ccRCC temporally according to systematic tracking of the dysregulated modules of reweighted Protein-Protein Interaction (PPI) networks. Methods. Firstly, normal and ccRCC PPI network were inferred and reweighted...

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Detalles Bibliográficos
Autores principales: Wang, Shao-Mei, Sun, Ze-Qiang, Li, Hong-Yun, Wang, Jin, Liu, Qing-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620417/
https://www.ncbi.nlm.nih.gov/pubmed/26543493
http://dx.doi.org/10.1155/2015/313740