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Environmental neurotoxin interaction with proteins: Dose-dependent increase of free and protein-associated BMAA (β-N-methylamino-L-alanine) in neonatal rat brain

β-Methylamino-L-alanine (BMAA) is implicated in the aetiology of neurodegenerative disorders. Neonatal exposure to BMAA induces cognitive impairments and progressive neurodegenerative changes including intracellular fibril formation in the hippocampus of adult rats. It is unclear why the neonatal hi...

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Detalles Bibliográficos
Autores principales: Karlsson, Oskar, Jiang, Liying, Ersson, Lisa, Malmström, Tim, Ilag, Leopold L., Brittebo, Eva B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620439/
https://www.ncbi.nlm.nih.gov/pubmed/26498001
http://dx.doi.org/10.1038/srep15570