Trypsin- and low pH-mediated fusogenicity of avian metapneumovirus fusion proteins is determined by residues at positions 100, 101 and 294

Avian metapneumovirus (aMPV) and human metapneumovirus (hMPV) are members of the genus Metapneumovirus in the subfamily Pneumovirinae. Metapneumovirus fusion (F) protein mediates the fusion of host cells with the virus membrane for infection. Trypsin- and/or low pH-induced membrane fusion is a strai...

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Detalles Bibliográficos
Autores principales: Yun, Bingling, Guan, Xiaolu, Liu, Yongzhen, Gao, Yanni, Wang, Yongqiang, Qi, Xiaole, Cui, Hongyu, Liu, Changjun, Zhang, Yanping, Gao, Li, Li, Kai, Gao, Honglei, Gao, Yulong, Wang, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620442/
https://www.ncbi.nlm.nih.gov/pubmed/26498473
http://dx.doi.org/10.1038/srep15584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620442/
https://www.ncbi.nlm.nih.gov/pubmed/26498473
http://dx.doi.org/10.1038/srep15584

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