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Trypsin- and low pH-mediated fusogenicity of avian metapneumovirus fusion proteins is determined by residues at positions 100, 101 and 294
Avian metapneumovirus (aMPV) and human metapneumovirus (hMPV) are members of the genus Metapneumovirus in the subfamily Pneumovirinae. Metapneumovirus fusion (F) protein mediates the fusion of host cells with the virus membrane for infection. Trypsin- and/or low pH-induced membrane fusion is a strai...
Autores principales: | Yun, Bingling, Guan, Xiaolu, Liu, Yongzhen, Gao, Yanni, Wang, Yongqiang, Qi, Xiaole, Cui, Hongyu, Liu, Changjun, Zhang, Yanping, Gao, Li, Li, Kai, Gao, Honglei, Gao, Yulong, Wang, Xiaomei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620442/ https://www.ncbi.nlm.nih.gov/pubmed/26498473 http://dx.doi.org/10.1038/srep15584 |
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