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Polyploid Titan Cells Produce Haploid and Aneuploid Progeny To Promote Stress Adaptation

Cryptococcus neoformans is a major life-threatening fungal pathogen. In response to the stress of the host environment, C. neoformans produces large polyploid titan cells. Titan cell production enhances the virulence of C. neoformans, yet whether the polyploid aspect of titan cells is specifically i...

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Detalles Bibliográficos
Autores principales: Gerstein, Aleeza C., Fu, Man Shun, Mukaremera, Liliane, Li, Zhongming, Ormerod, Kate L., Fraser, James A., Berman, Judith, Nielsen, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620463/
https://www.ncbi.nlm.nih.gov/pubmed/26463162
http://dx.doi.org/10.1128/mBio.01340-15