Cargando…

Knockout of Epstein-Barr Virus BPLF1 Retards B-Cell Transformation and Lymphoma Formation in Humanized Mice

BPLF1 of Epstein-Barr virus (EBV) is classified as a late lytic cycle protein but is also found in the viral tegument, suggesting its potential involvement at both initial and late stages of viral infection. BPLF1 possesses both deubiquitinating and deneddylating activity located in its N-terminal d...

Descripción completa

Detalles Bibliográficos
Autores principales: Whitehurst, Christopher B., Li, Guangming, Montgomery, Stephanie A., Montgomery, Nathan D., Su, Lishan, Pagano, Joseph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620474/
https://www.ncbi.nlm.nih.gov/pubmed/26489865
http://dx.doi.org/10.1128/mBio.01574-15