Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations

Tauopathies, such as Alzheimer’s disease, some cases of frontotemporal dementia, corticobasal degeneration and progressive supranuclear palsy, are characterized by aggregates of the microtubule-associated protein tau, which are linked to neuronal death and disease development and can be caused by mu...

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Detalles Bibliográficos
Autores principales: Iovino, Mariangela, Agathou, Sylvia, González-Rueda, Ana, Del Castillo Velasco-Herrera, Martin, Borroni, Barbara, Alberici, Antonella, Lynch, Timothy, O’Dowd, Sean, Geti, Imbisaat, Gaffney, Daniel, Vallier, Ludovic, Paulsen, Ole, Káradóttir, Ragnhildur Thóra, Spillantini, Maria Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620511/
https://www.ncbi.nlm.nih.gov/pubmed/26220942
http://dx.doi.org/10.1093/brain/awv222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620511/
https://www.ncbi.nlm.nih.gov/pubmed/26220942
http://dx.doi.org/10.1093/brain/awv222

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