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Iatrogenic CJD due to pituitary-derived growth hormone with genetically determined incubation times of up to 40 years

Patients with iatrogenic Creutzfeldt-Jakob disease due to administration of cadaver-sourced growth hormone during childhood are still being seen in the UK 30 years after cessation of this treatment. Of the 77 patients who have developed iatrogenic Creutzfeldt-Jakob disease, 56 have been genotyped. T...

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Detalles Bibliográficos
Autores principales: Rudge, Peter, Jaunmuktane, Zane, Adlard, Peter, Bjurstrom, Nina, Caine, Diana, Lowe, Jessica, Norsworthy, Penny, Hummerich, Holger, Druyeh, Ron, Wadsworth, Jonathan D. F., Brandner, Sebastian, Hyare, Harpreet, Mead, Simon, Collinge, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620512/
https://www.ncbi.nlm.nih.gov/pubmed/26268531
http://dx.doi.org/10.1093/brain/awv235