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Selective vulnerability of Rich Club brain regions is an organizational principle of structural connectivity loss in Huntington’s disease

Huntington’s disease can be predicted many years before symptom onset, and thus makes an ideal model for studying the earliest mechanisms of neurodegeneration. Diffuse patterns of structural connectivity loss occur in the basal ganglia and cortex early in the disease. However, the organizational pri...

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Detalles Bibliográficos
Autores principales: McColgan, Peter, Seunarine, Kiran K., Razi, Adeel, Cole, James H., Gregory, Sarah, Durr, Alexandra, Roos, Raymund A. C., Stout, Julie C., Landwehrmeyer, Bernhard, Scahill, Rachael I., Clark, Chris A., Rees, Geraint, Tabrizi, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620513/
https://www.ncbi.nlm.nih.gov/pubmed/26384928
http://dx.doi.org/10.1093/brain/awv259