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Selective vulnerability of Rich Club brain regions is an organizational principle of structural connectivity loss in Huntington’s disease
Huntington’s disease can be predicted many years before symptom onset, and thus makes an ideal model for studying the earliest mechanisms of neurodegeneration. Diffuse patterns of structural connectivity loss occur in the basal ganglia and cortex early in the disease. However, the organizational pri...
Autores principales: | McColgan, Peter, Seunarine, Kiran K., Razi, Adeel, Cole, James H., Gregory, Sarah, Durr, Alexandra, Roos, Raymund A. C., Stout, Julie C., Landwehrmeyer, Bernhard, Scahill, Rachael I., Clark, Chris A., Rees, Geraint, Tabrizi, Sarah J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620513/ https://www.ncbi.nlm.nih.gov/pubmed/26384928 http://dx.doi.org/10.1093/brain/awv259 |
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