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Trans-presentation of IL-15 modulates STAT5 activation and Bcl-6 expression in T(H)1 cells

During infection, naïve CD4(+) T helper cells differentiate into specialized effector subsets based upon environmental signals propagated by the cytokine milieu. Recently, this paradigm has been complicated by the demonstration that alterations in the cytokine environment can result in varying degre...

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Detalles Bibliográficos
Autores principales: Cooley, Ian D., Read, Kaitlin A., Oestreich, Kenneth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620557/
https://www.ncbi.nlm.nih.gov/pubmed/26500048
http://dx.doi.org/10.1038/srep15722