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Exceptionally large entropy contributions enable the high rates of GTP hydrolysis on the ribosome
Protein synthesis on the ribosome involves hydrolysis of GTP in several key steps of the mRNA translation cycle. These steps are catalyzed by the translational GTPases of which elongation factor Tu (EF-Tu) is the fastest GTPase known. Here, we use extensive computer simulations to explore the origin...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620562/ https://www.ncbi.nlm.nih.gov/pubmed/26497916 http://dx.doi.org/10.1038/srep15817 |