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Integrated analysis of genome-wide DNA methylation, gene expression and protein expression profiles in molecular subtypes of WHO II-IV gliomas

BACKGROUND: Glioma is the most common malignant primary brain tumor among adults, among which glioblastoma (GBM) exhibits the highest malignancy. Despite current standard chemoradiation, glioma is still invariably fatal. A further insight into the molecular background of glioma is required to improv...

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Detalles Bibliográficos
Autores principales: Wang, Zhi-Liang, Zhang, Chuan-Bao, Cai, Jin-Quan, Li, Qing-Bin, Wang, Zheng, Jiang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620600/
https://www.ncbi.nlm.nih.gov/pubmed/26502731
http://dx.doi.org/10.1186/s13046-015-0249-z