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Pax3-induced expansion enables the genetic correction of dystrophic satellite cells

BACKGROUND: Satellite cells (SCs) are indispensable for muscle regeneration and repair; however, due to low frequency in primary muscle and loss of engraftment potential after ex vivo expansion, their use in cell therapy is currently unfeasible. To date, an alternative to this limitation has been th...

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Detalles Bibliográficos
Autores principales: Filareto, Antonio, Rinaldi, Fabrizio, Arpke, Robert W., Darabi, Radbod, Belanto, Joseph J., Toso, Erik A., Miller, Auston Z., Ervasti, James M., McIvor, R. Scott, Kyba, Michael, Perlingeiro, Rita CR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620645/
https://www.ncbi.nlm.nih.gov/pubmed/26504514
http://dx.doi.org/10.1186/s13395-015-0061-7