Cargando…
Pax3-induced expansion enables the genetic correction of dystrophic satellite cells
BACKGROUND: Satellite cells (SCs) are indispensable for muscle regeneration and repair; however, due to low frequency in primary muscle and loss of engraftment potential after ex vivo expansion, their use in cell therapy is currently unfeasible. To date, an alternative to this limitation has been th...
Autores principales: | Filareto, Antonio, Rinaldi, Fabrizio, Arpke, Robert W., Darabi, Radbod, Belanto, Joseph J., Toso, Erik A., Miller, Auston Z., Ervasti, James M., McIvor, R. Scott, Kyba, Michael, Perlingeiro, Rita CR |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620645/ https://www.ncbi.nlm.nih.gov/pubmed/26504514 http://dx.doi.org/10.1186/s13395-015-0061-7 |
Ejemplares similares
-
An ex vivo Gene Therapy Approach to Treat Muscular Dystrophy Using inducible Pluripotent Stem Cells
por: Filareto, Antonio, et al.
Publicado: (2013) -
Pax7 remodels the chromatin landscape in skeletal muscle stem cells
por: Lilja, Karin C., et al.
Publicado: (2017) -
Expansion and Purification Are Critical for the Therapeutic Application of Pluripotent Stem Cell-Derived Myogenic Progenitors
por: Kim, Jaemin, et al.
Publicado: (2017) -
A Perspective on the Potential of Human iPS Cell-Based Therapies for Muscular Dystrophies: Advancements so far and Hurdles to Overcome
por: Darabi, Radbod, et al.
Publicado: (2013) -
Membrane-stabilizing copolymers confer marked protection to dystrophic skeletal muscle in vivo
por: Houang, Evelyne M, et al.
Publicado: (2015)