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Cardiac Bmi1(+) cells contribute to myocardial renewal in the murine adult heart

INTRODUCTION: The mammalian adult heart maintains a continuous, low cardiomyocyte turnover rate throughout life. Although many cardiac stem cell populations have been studied, the natural source for homeostatic repair has not yet been defined. The Polycomb protein BMI1 is the most representative mar...

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Detalles Bibliográficos
Autores principales: Valiente-Alandi, Iñigo, Albo-Castellanos, Carmen, Herrero, Diego, Arza, Elvira, Garcia-Gomez, Maria, Segovia, José C., Capecchi, Mario, Bernad, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620653/
https://www.ncbi.nlm.nih.gov/pubmed/26503423
http://dx.doi.org/10.1186/s13287-015-0196-9