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A Generalized Entropy Measure of Within-Host Viral Diversity for Identifying Recent HIV-1 Infections

There is a need for incidence assays that accurately estimate HIV incidence based on cross-sectional specimens. Viral diversity-based assays have shown promises but are not particularly accurate. We hypothesize that certain viral genetic regions are more predictive of recent infection than others an...

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Detalles Bibliográficos
Autores principales: Wu, Julia Wei, Patterson-Lomba, Oscar, Novitsky, Vladimir, Pagano, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620842/
https://www.ncbi.nlm.nih.gov/pubmed/26496342
http://dx.doi.org/10.1097/MD.0000000000001865