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Correlation of baseline biomarkers with clinical outcomes and response to fulvestrant with vandetanib or placebo in patients with bone predominant metastatic breast cancer: An OCOG ZAMBONEY sub-study

BACKGROUND: Bone metastases are common in women with breast cancer and often result in skeletal related events (SREs). As the angiogenic factor vascular endothelial growth factor (VEGF) regulates osteoclast activity and is associated with more extensive bone metastases and SRE risk in metastatic bre...

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Detalles Bibliográficos
Autores principales: Addison, Christina L., Pond, Gregory R., Cochrane, Brandy, Zhao, Huijun, Chia, Stephen K., Levine, Mark N., Clemons, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620970/
https://www.ncbi.nlm.nih.gov/pubmed/26579488
http://dx.doi.org/10.1016/j.jbo.2015.04.001