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Micro Regional Heterogeneity of (64)Cu-ATSM and (18)F-FDG Uptake in Canine Soft Tissue Sarcomas: Relation to Cell Proliferation, Hypoxia and Glycolysis

OBJECTIVES: Tumour microenvironment heterogeneity is believed to play a key role in cancer progression and therapy resistance. However, little is known about micro regional distribution of hypoxia, glycolysis and proliferation in spontaneous solid tumours. The overall aim was simultaneous investigat...

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Detalles Bibliográficos
Autores principales: Zornhagen, Kamilla Westarp, Hansen, Anders E., Oxboel, Jytte, Clemmensen, Andreas E., El Ali, Henrik H., Kristensen, Annemarie T., Kjær, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621038/
https://www.ncbi.nlm.nih.gov/pubmed/26501874
http://dx.doi.org/10.1371/journal.pone.0141379