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Differential regulation of human Eag1 channel expression by serum and epidermal growth factor in lung and breast cancer cells

Oncogenic ether à-go-go-1 (Eag1) potassium channels are overexpressed in most primary human solid tumors. Low oxygen and nutrient/growth factor concentrations play critical roles in tumorigenesis. However, the mechanisms by which tumor cells survive and proliferate under growth factor-depleted condi...

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Detalles Bibliográficos
Autores principales: Acuña-Macías, Isabel, Vera, Eunice, Vázquez-Sánchez, Alma Yolanda, Mendoza-Garrido, María Eugenia, Camacho, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621197/
https://www.ncbi.nlm.nih.gov/pubmed/26527881
http://dx.doi.org/10.2147/OTT.S85504