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Differential regulation of human Eag1 channel expression by serum and epidermal growth factor in lung and breast cancer cells
Oncogenic ether à-go-go-1 (Eag1) potassium channels are overexpressed in most primary human solid tumors. Low oxygen and nutrient/growth factor concentrations play critical roles in tumorigenesis. However, the mechanisms by which tumor cells survive and proliferate under growth factor-depleted condi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621197/ https://www.ncbi.nlm.nih.gov/pubmed/26527881 http://dx.doi.org/10.2147/OTT.S85504 |