Luteolin decreases invasiveness, deactivates STAT3 signaling, and reverses interleukin-6 induced epithelial–mesenchymal transition and matrix metalloproteinase secretion of pancreatic cancer cells

Luteolin, a flavone, has been shown to exhibit anticancer properties. Here, we investigated whether luteolin affects epithelial–mesenchymal transition (EMT) and invasiveness of pancreatic cancer cell lines and their underlying mechanism. Pancreatic cancer cell lines PANC-1 and SW1990 were used in ou...

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Detalles Bibliográficos
Autores principales: Huang, Xince, Dai, Shengjie, Dai, Juji, Xiao, Yuwu, Bai, Yongyu, Chen, Bicheng, Zhou, Mengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621199/
https://www.ncbi.nlm.nih.gov/pubmed/26527884
http://dx.doi.org/10.2147/OTT.S91511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621199/
https://www.ncbi.nlm.nih.gov/pubmed/26527884
http://dx.doi.org/10.2147/OTT.S91511

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