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Carcinogenic Liver Fluke Secretes Extracellular Vesicles That Promote Cholangiocytes to Adopt a Tumorigenic Phenotype

Background. Throughout Asia, there is an unprecedented link between cholangiocarcinoma and infection with the liver fluke Opisthorchis viverrini. Multiple processes, including chronic inflammation and secretion of parasite proteins into the biliary epithelium, drive infection toward cancer. Until no...

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Detalles Bibliográficos
Autores principales: Chaiyadet, Sujittra, Sotillo, Javier, Smout, Michael, Cantacessi, Cinzia, Jones, Malcolm K., Johnson, Michael S., Turnbull, Lynne, Whitchurch, Cynthia B., Potriquet, Jeremy, Laohaviroj, Marut, Mulvenna, Jason, Brindley, Paul J., Bethony, Jeffrey M., Laha, Thewarach, Sripa, Banchob, Loukas, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621255/
https://www.ncbi.nlm.nih.gov/pubmed/25985904
http://dx.doi.org/10.1093/infdis/jiv291