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Defects in the COG complex and COG-related trafficking regulators affect neuronal Golgi function

The Conserved Oligomeric Golgi (COG) complex is an evolutionarily conserved hetero-octameric protein complex that has been proposed to organize vesicle tethering at the Golgi apparatus. Defects in seven of the eight COG subunits are linked to Congenital Disorders of Glycosylation (CDG)-type II, a fa...

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Detalles Bibliográficos
Autores principales: Climer, Leslie K., Dobretsov, Maxim, Lupashin, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621299/
https://www.ncbi.nlm.nih.gov/pubmed/26578865
http://dx.doi.org/10.3389/fnins.2015.00405