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The molecular mechanism of nuclear transport revealed by atomic-scale measurements

Nuclear pore complexes (NPCs) form a selective filter that allows the rapid passage of transport factors (TFs) and their cargoes across the nuclear envelope, while blocking the passage of other macromolecules. Intrinsically disordered proteins (IDPs) containing phenylalanyl-glycyl (FG)-rich repeats...

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Detalles Bibliográficos
Autores principales: Hough, Loren E, Dutta, Kaushik, Sparks, Samuel, Temel, Deniz B, Kamal, Alia, Tetenbaum-Novatt, Jaclyn, Rout, Michael P, Cowburn, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621360/
https://www.ncbi.nlm.nih.gov/pubmed/26371551
http://dx.doi.org/10.7554/eLife.10027