Early aggregation preceding the nucleation of insulin amyloid fibrils as monitored by small angle X-ray scattering

The nucleation event of amyloid fibrils is one of the most crucial processes that dictate the timing and rate of the pathology of diseases; however, information regarding how protein molecules associate to produce fibril nuclei is currently limited. In order to explore this issue in more detail, we...

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Detalles Bibliográficos
Autores principales: Chatani, Eri, Inoue, Rintaro, Imamura, Hiroshi, Sugiyama, Masaaki, Kato, Minoru, Yamamoto, Masahide, Nishida, Koji, Kanaya, Toshiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621412/
https://www.ncbi.nlm.nih.gov/pubmed/26503463
http://dx.doi.org/10.1038/srep15485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621412/
https://www.ncbi.nlm.nih.gov/pubmed/26503463
http://dx.doi.org/10.1038/srep15485

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