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Mechanisms of mutational robustness in transcriptional regulation

Robustness is the invariance of a phenotype in the face of environmental or genetic change. The phenotypes produced by transcriptional regulatory circuits are gene expression patterns that are to some extent robust to mutations. Here we review several causes of this robustness. They include robustne...

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Detalles Bibliográficos
Autores principales: Payne, Joshua L., Wagner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621482/
https://www.ncbi.nlm.nih.gov/pubmed/26579194
http://dx.doi.org/10.3389/fgene.2015.00322